GLOW & REPAIR
Polynucleotide injections.
We’ll walk you through everything you need to know about our polynucleotide injection treatments. Polynucleotides are like tiny building blocks found in your body. They’re made up of different parts, including a phosphate group, a sugar and a base. You can think of them as Lego pieces that join together to form longer structures called nucleic acids, such as DNA and RNA. They provide instructions, fix any damage and keep your skin cells functioning properly. As you age, changes in these instructions can contribute to visible signs of ageing, such as wrinkles and sagging skin. Whether you're looking to enhance skin hydration, improve texture, or target signs of aging, we’ll guide you on how polynucleotides can rejuvenate your skin at the molecular level. These treatments promote healing, boost collagen production and restore radiance, leaving you with a refreshed, youthful complexion.
With personalised options tailored to your skin’s unique needs, we’ll ensure you feel confident in choosing the perfect solution for glowing, revitalised skin.
HOW IT WORKS
Restored confidence is just a few steps away.
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BOOK YOUR CONSULTATION
Reach out below to select the best day and time for us to assess your skin and get this party started
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WE'LL CREATE YOUR PERSONALISED SKIN BLEND
Based on your skin type, concerns and goals, we’ll create a treatment plan that focuses on safety and results.
GET READY FOR THE RESULT
No matter the length of your plan, we’ll work together to achieve ultimate skin goals.
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Nucleofill
What is Nucleofill and how does it work?
Nucleofill is a mesotherapy product. It deeply renews and intervenes in skin biorestructuring. Nucleofill offers a rejuvenating effect that is multiplied and long-lasting. The polynucleotides concentrated in this product effectively activate cell renewal in a sustainable and preventive manner. The production of collagen and elastin is stimulated, which leads to a thickening and lifting of the skin. This product creates a powerful anti-oxidant action. The skin gains in deep hydration and firmness. This product is indicated for skin exposed to stress, lack of oxygen, dehydrated skin, stretch marks, scars.These injections reduce facial wrinkles and thanks to its antioxidant and moisturising properties a lifting effect is visible.
The benefits
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Visible rejuvenating effect without affecting facial features
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Polynucleotides help to stimulate cell renewal
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Acts on three levels: lifting, antioxidant, moisturising
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Reduces the appearance of wrinkles, helping to firm the skin
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Rehydrates dehydrated skin
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Before injections, to extend their aesthetic effects
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Biostimulation and increase in collagen type 1
TREATMENT TIME
20 minutes


What areas can be treated with Nucleofill?
Nucleofill comes in three varieties. The soft gel is suitable for use around the delicate eye area, addressing crow’s feet, eye bags and lost volume. Medium gel addresses thinner skin, such as crepey skin on the neck, and the strong formula treats more robust areas of skin, including the treatment of stretch marks.Treatment areas include: small scars, very thin lines, bio-restructuration of deep tissues, re-densification of the dermo-epidermal tissue, improvement of superficial wrinkles without the use of fillers
How many treatments are needed?
Generally, a course of two to three sessions, spaced about four weeks apart, is recommended for optimal results.
How do I maintain my results?
Maintenance sessions every 6 to 12 months are advised to sustain the benefits and keep your skin looking rejuvenated.
Is Nucleofill safe, and who is it suitable for?
Nucleofill is suitable for individuals looking to improve skin elasticity, hydration, and reduce signs of aging such as fine lines and wrinkles. It is ideal for both men and women of various skin types, especially those in need of deep skin repair or regeneration.
How much does it cost?
Nucleofill treatments prices start from £270. Most clients begin with two treatments, spaced four weeks apart and may opt to continue with a course of 3 to 4.
Vitaran
What is Vitaran and how does it work?
VITARAN is one of the leading brands in the innovative new wave of aesthetic products known as polynucleotides. An advanced skin treatment created using highly purified fragments of trout DNA, VITARAN is bio-revitalising skin injectable containing anti-inflammatory properties.
VITARAN I is derived from ultra-purified and sterilised salmon trout DNA. Acting as a bio-stimulator, VITARAN I repairs and regenerates skin cells on a cellular level. The result is a brighter, youthful complexion with reduced signs of ageing, texture, wrinkles, dullness, and more. VITARAN I is perfect for use in the periorbital area and for skin laxity.
VITARAN II acts as a powerful bio-stimulator to promote cellular repair and regeneration. Tailored for larger treatment areas, such as the face, neck, hands, and body, it targets key signs of ageing, such as skin laxity, uneven texture, and dullness, leaving the skin plumper, tighter, smoother, and visibly rejuvenated.
The benefits
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VITARAN I, Indicated for the improvement of periocular wrinkles
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Formulated with highly filtered, ultra-purified, sterilised trout DNA
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Can be used alongside other injectables (as long as VITARAN is not injected in the same area as the other injectables), including skin boosters such as Seventy Hyal 2000.
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Anti-inflammatory properties
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Combats free radical damage
TREATMENT TIME
20 minutes


What areas can be treated with Vitaran?
VITARAN I is intended for use on the under eye (periorbital area), and VITARAN II is intended for use on the face.
How many treatments are needed?
Generally, a course of two to three sessions, spaced about four weeks apart, is recommended for optimal results.
How do I maintain my results?
Following the initial two treatment sessions, we recommend one session every six months to maintain and enhance the results.
Is Vitaran safe, and who is it suitable for?
Vitaran is typically recommended for individuals aged 30 and above, as this is when the skin begins to show early signs of aging, such as fine lines, dehydration, and loss of elasticity. However, it can also be suitable for those in their 20s who are looking to proactively repair and maintain skin health. For older individuals, Vitaran can help address more advanced signs of aging, like deeper wrinkles and significant skin damage.
How much does it cost?
Vitaran treatments prices start from £280. Most clients begin with two treatments, spaced four weeks apart and may opt to continue with a course of 3 to 4.
Plinest
What is Plinest and how does it work?
Plinest® is an injectable polynucleotide product aimed at improving skin texture, rejuvenation and hair loss.
Polynucleotides are deoxyribonucleotide polymers (DNA fragments) extracted from fish, sterilised and ultra-purified to injectable products. Polynucleotides promote DNA synthesis, improve cell regeneration and cellular repair. They increase blood flow and nutrient supply to the cells. They also have additional benefits including anti-inflammatory and antioxidant properties. Collectively, these benefits lead to an overall improved skin quality. When the treatment is done on the scalp, it leads to an improved scalp skin quality and increased hair growth. They play a crucial role in improving skin quality and promoting bio-regeneration.
The benefits
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Reduce the signs of ageing.
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Restore injured cells and tissues.
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Increase moisture in the skin and resilience.
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Naturally, rebuild your skin’s protection.
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Enhance the skin’s suppleness, texture, tone, and vibrancy.
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It addresses fine lines, wrinkles, volume loss, dull, dry, sensitive skin, acne scars, hyperpigmentation, and enlarged pores.
TREATMENT TIME
20 minutes


What areas can be treated with Plinest?
Plinest is a highly versatile treatment suitable for:
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Face: Under the eyes, cheekbones, and jawline.
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Neck and Décolletage: Tightens and rejuvenates sagging skin.
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Hair: Improves hair density and scalp health.
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Lips and Eyebrows: Enhances skin texture and appearance in delicate areas.
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Body: Inner arms and thighs for firmer, hydrated skin.
How many treatments are needed?
Prevention treatment for younger skin: 3 intradermal treatments - one every 3 weeks - followed by a maintenance treatment every 2-3 months
Recovery treatment for ageing skin: 4 infiltrations treatment, one every 1-2 weeks, followed by maintenance sessions every 1-3 month
Is Plinest safe, and who is it suitable for?
Plinest is suitable for individuals who are looking to address signs of aging, improve skin texture, and restore elasticity. It is particularly effective for those with skin showing early to moderate signs of aging, such as fine lines, wrinkles, and loss of firmness. Suitable for various skin types, it is ideal for individuals aged 30 and above.
How much does it cost?
Plinest treatments prices start from £290. Most clients begin with 2-4 treatments, spaced 1 to 4 weeks apart.
Newest
What is Newest and how does it work?
Mastelli's latest polynucleotide-based product is NEWEST, an injectable gel that combines polynucleotides with hyaluronic acid. This innovative formulation works at the cellular level to repair tissue and enhance skin quality, making it particularly effective for mature and dehydrated skin. NEWEST promotes skin regeneration, improves elasticity, and reduces signs of aging such as fine lines and wrinkles. It is suitable for use on the face, neck, and décolletage.
The benefits
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Newly improved skin quality
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Restored radiance
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Reversed signs of aging.
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Reduced fine lines, wrinkles,
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Increased volume
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Reduced acne scars, hyperpigmentation and enlarged pores.
TREATMENT TIME
20 minutes


What areas can be treated with Newest?
Newest is primarily for more mature and dehydrated skin. It can be injected into the face, neck & decollette.
How many treatments are needed?
For NEWEST, the recommended treatment regimen typically consists of 2-4 sessions spaced about 1-4 weeks apart. This allows the polynucleotides to stimulate collagen production and repair the skin over time. After the initial treatments, maintenance sessions are generally recommended every 6-12 months, depending on your skin's needs and the results you're aiming to achieve.
Is Newest safe, and who is it suitable for?
It is made from polynucleotides and hyaluronic acid, both of which are biocompatible and well-tolerated by the body. NEWEST is suitable for individuals looking to repair skin damage, improve hydration, and address signs of aging such as fine lines, wrinkles, and skin laxity. It is ideal for people aged 30 and above, especially those with mature or dehydrated skin. However, it can also benefit younger individuals looking to enhance skin quality and prevent early signs of aging.
How much does it cost?
Newest treatments prices start from £290. Most clients begin with 2-4 treatments, spaced 1 to 4 weeks apart.
BUT FIRST, OUR CONSULTATION POLICY
New to Bambú spa & skin clinic?
To help you reach your glowing skin goals, we all have to start somewhere. Which is why we ask prospective clients to begin with a 1:1 consultation with us before diving into a regimen. This helps us assess your skin, your concerns and your unique goals to create a plan of action just for you.

FLEXIBLE PAYMENT OPTIONS
For your perfect treatment packages.
*For inquiries regarding flexible payment options for individual treatments, please contact the clinic directly.